Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants with Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Trial Identifier:	D9803C00001
Sponsor:	AstraZeneca
Start Date:	February 2026
Primary Completion Date:	August 2029
Study Completion Date:	October 2031
Condition:	Esophageal cancer; Gastric Cancer

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Trial Locations

Country	Location
AU	Darlinghurst, AU, 2010
AU	Garran, AU, 2605
AU	Heidelberg, AU, 3084
AU	Murdoch, AU, 6150
AU	Randwick, AU, 2031
AU	Westmead, AU, 2145
BE	Brussel, BE, 1200
BE	Edegem, BE, 2650
BE	Gent, BE, 9000
BE	Leuven, BE, 3000
BR	Barretos, BR, 14784-400
BR	Fortaleza, BR, 60336-045
BR	Natal, BR, 59075-740
BR	Porto Alegre, BR, 91350200
BR	Salvador, BR, 41.950-610
BR	Santa Maria, BR, 97015-450
BR	São Paulo, BR, 01246-000
BR	Vitoria, BR, 29043-260
CA, AB	Edmonton, AB, CA, T6G 1Z2
CA, BC	Abbotsford, BC, CA, V2S0C2
CA, BC	Vancouver, BC, CA, VSZ 4E6
CA, Manitoba	Winnipeg, Manitoba, CA, R3E 0V9
CA, ON	Brampton, ON, CA, L6R 3J7
CA, ON	Ottawa, ON, CA, K1H 8L6
CA, ON	Toronto, ON, CA, M5G 2M9
CA, ON	Toronto, ON, CA, M4N 3M5
CA, QC	Montréal, QC, CA, H3A 1A1
CA, QC	Québec, QC, CA, G1J 1Z4
CN	Beijing, CN, 102200
CN	Beijing, CN, 100050
CN	Beijing, CN, 100142
CN	Beijing, CN, 100032
CN	Changde, CN, 415000
CN	Chengdu, CN, 610041
CN	chongqing, CN, 400016
CN	fuzhou, CN, 350005
CN	fuzhou, CN, 350011
CN	Guangzhou, CN, 510655
CN	Hangzhou, CN, 310014
CN	Hangzhou, CN, 310020
CN	Hangzhou, CN, 310003
CN	Harbin, CN, 150081
CN	Hefei, CN, 230031
CN	Huhhot, CN, 010020
CN	Ji Nan, CN, 2501117
CN	Kunming, CN, 650118
CN	lanzhou, CN, 730000
CN	Linhai, CN, 317000
CN	Linyi, CN, 276000
CN	nanchang, CN, 330029
CN	Nanchang, CN, 330000
CN	Nanjing, CN, 2100008
CN	Nanjing, CN, 210029
CN	Nanning, CN, 530021
CN	Nantong, CN, 226361
CN	shanghai, CN, 200025
CN	Shanghai, CN, 200127
CN	Shanghai, CN, 20032
CN	Shantou, CN, 515041
CN	Shenyang, CN, 110016
CN	Shenzhen, CN, 518036
CN	Tianjin, CN, 300050
CN	Wuhan, CN, 430079
CN	Wuhan City, CN, 430030
CN	Xiamen, CN, 361003
CN	Xi'An, CN, 710068
CN	Xingtai, CN, 054031
CN	Xuzhou, CN, 221009
CN	Yinchuan, CN, 750004
CN	Zhengzhou, CN, 450008
DE	Augsburg, DE, 86156
DE	Berlin, DE, 13353
DE	Bonn, DE, 53127
DE	Essen, DE, 45122
DE	Frankfurt, DE, 60488
DE	Freiburg, DE, 79106
DE	Hamburg, DE, 20249
DE	Heilbronn, DE, 74078
DE	Leipzig, DE, 04103
DE	Mainz, DE, 55131
DE	Moers, DE, 47441
DE	München, DE, 81657
DE	Stuttgart, DE, 70376
DE	Ulm, DE, 89081
ES	Barcelona, ES, 08035
ES	Barcelona, ES, 8036
ES	Madrid, ES, 28041
ES	Pamplona, ES, 31008
ES	Santander, ES, 39008
ES	Santiago de Compostela, ES, 15706
ES	Valencia, ES, 46010
GB	Cambridge, GB, CB2 0QQ
GB	Dundee, GB, DD1 9SY
GB	Leeds, GB, LS9 7TF
GB	London, GB, EC1A 7BE
GB	Manchester, GB, M20 4BX
GB	Oxford, GB, OX3 7LE
HU	Budapest, HU, 1122
HU	Budapest, HU, 1083
HU	Debrecen, HU, 4032
HU	Győr, HU, 9024
HU	Gyula, HU, 5700
HU	Nyíregyháza, HU, 4400
HU	Pécs, HU, 7624
HU	Zalaegerszeg, HU, 8900
IN	Ahmedabad, IN, 380060
IN	Bhubaneshwar, IN, 751019
IN	Hyderabad, IN, 500032
IN	Mohali, IN, 160055
IN	Mumbai, IN, 400012
IN	New Delhi, IN, 110017
IN	New Delhi, IN, 110060
IN	Vijayawada, IN, 520002
IT	MELDOLA, IT, 47014
IT	Milano, IT, 20133
IT	Milano, IT, 20162
IT	Milano, IT, 20141
IT	Padova, IT, 35128
IT	Rozzano, IT, 20089
IT	Tricase, IT, 73039
JP	Hirakata-shi, JP, 573-1191
JP	Kashiwa, JP, 277-8577
JP	Kitaadachi-gun, JP, 362-0806
JP	Koto-ku, JP, 135-8550
JP	Kurashiki-shi, JP, 710-8602
JP	Niigata-shi, JP, 951-8566
JP	Osaka-shi, JP, 541-8567
JP	Sakai, JP, 590-0197
JP	Sunto-gun, JP, 411-8777
JP	Yokohama-shi, JP, 232-0024
KR	Daegu, KR, 41404
KR	Hwasun-gun, KR, 58128
KR	Seongnam-si, KR, 13620
KR	Seoul, KR, 03080
KR	Seoul, KR, 05505
KR	Seoul, KR, 06351
KR	Seoul, KR, 03722
KR	Seoul, KR, 06591
PL	Gdańsk, PL, 80-219
PL	Koszalin, PL, 75-581
PL	Kraków, PL, 31-501
PL	Lublin, PL, 20-080
PL	Olsztyn, PL, 10-228
PL	Warszawa, PL, 02-034
TH	Bangkok, TH, 10700
TH	Bangkok, TH, 10210
TH	Dusit, TH, 10300
TH	Hat Yai, TH, 90110
TH	Hatyai, TH, 90110
TH	Khon-Kaen, TH, 40002
TH	Muang, TH, 22000
TH	Muang, TH, 70000
TR	Ankara, TR, 06530
TR	Antalya, TR, 07100
TR	İstanbul, TR, 34854
TR	İstanbul, TR, 34098
TR	Sahinbey, TR, 27310
TR	Yüregir, TR, 01250
TW	Kaohsiung, TW, 80756
TW	Kaohsiung, TW, 83301
TW	Taichung, TW
TW	Taichung, TW, 40447
TW	Tainan, TW, 704
TW	Taipei, TW, 10002
TW	Taipei, TW, 112
TW	Taoyuan, TW, 333
US, AZ	Phoenix, AZ, US, 85054
US, CA	Duarte, CA, US, 91010
US, CA	La Jolla, CA, US, 92093
US, CA	Orange, CA, US, 92868
US, CA	Walnut Creek, CA, US, 94598
US, CO	Lone Tree, CO, US, 80124
US, DE	Newark, DE, US, 19713
US, FL	Fort Myers, FL, US, 33901
US, FL	Jacksonville, FL, US, 32224
US, FL	Saint Petersburg, FL, US, 33705
US, FL	West Palm Beach, FL, US, 33401
US, GA	Atlanta, GA, US, 30322
US, GA	Atlanta, GA, US, 30309
US, IL	Chicago, IL, US, 60637
US, IL	Niles, IL, US, 60714
US, KY	Lexington, KY, US, 40536
US, KY	Louisville, KY, US, 40207
US, MA	Boston, MA, US, 02114
US, MI	Grand Rapids, MI, US, 49503
US, MN	Burnsville, MN, US, 55337
US, MN	Rochester, MN, US, 55905
US, MO	Kansas City, MO, US, 64132
US, MO	Saint Louis, MO, US, 63110
US, NC	Winston Salem, NC, US, 27103
US, NJ	East Brunswick, NJ, US, 08816
US, NJ	Hackensack, NJ, US, 07601
US, NJ	Summit, NJ, US, 07901
US, NY	Bronx, NY, US, 10461
US, NY	Bronx, NY, US, 10468
US, NY	New York, NY, US, 10065
US, NY	New York, NY, US, 10032
US, NY	New York, NY, US, 10029
US, OH	Columbus, OH, US, 43221
US, OR	Portland, OR, US, 97239
US, OR	Portland, OR, US, 97213
US, PA	Hershey, PA, US, 17033
US, PA	Philadelphia, PA, US, 19104
US, PA	Pittsburgh, PA, US, 15232
US, PA	Pittsburgh, PA, US, 15240
US, PA	Wilkes Barre, PA, US, 18711
US, PR	San Juan, PR, US, 00921
US, SD	Sioux Falls, SD, US, 57105
US, TN	Memphis, TN, US, 38104
US, TN	Nashville, TN, US, 37203
US, TX	Dallas, TX, US, 75246
US, TX	Sherman, TX, US, 75090
US, VA	Blacksburg, VA, US, 24060
US, VA	Fairfax, VA, US, 22031
US, VA	Fort Belvoir, VA, US, 22060
US, VA	Richmond, VA, US, 23219
US, WA	Seattle, WA, US, 98104
US, WV	Charleston, WV, US, 25315