A Study to Investigate the Efficacy and Safety of Dato-DXd with or without Osimertinib Compared with Platinum Based Doublet Chemotherapy in Participants with EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Trial Identifier: D516KC00001
Sponsor: AstraZeneca
Collaborator:
Daiichi Sankyo
Start Date: October 2024
Primary Completion Date: September 2026
Study Completion Date: September 2028

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

No documents have been posted yet.

Trial Locations

Country Location
AU Fitzroy, AU, VIC3065
AU Heidelberg, AU, 3084
AU Kogarah, AU, 2217
AU Liverpool, AU, 2170
AU Nedlands, AU, 6009
AU Port Macquarie, AU, 2444
AU St Leonards, AU, 2065
AU Westmead, AU, 2145
AU Woodville, AU, 5011
AU Woolloongabba, AU, 4102
BE Charleroi, BE, 6060
BE Edegem, BE, 2650
BE Gent, BE, 9000
BE Ghent, BE, 9000
BE Hasselt, BE, 3500
BE Jette, BE, 1090
BE La Louvière, BE, 7100
BE Leuven, BE, 3000
BE Namur, BE, 5000
BE Roeselare, BE, 8800
BR Barretos, BR, 14784-400
BR Betim, BR, 32671-550
BR Blumenau, BR, 89010-340
BR Florianópolis, BR, 88040-970
BR Itajai, BR, 88301-220
BR Pelotas, BR, 96020-080
BR Porto Alegre, BR, 90610-000
BR Porto Alegre, BR, 90470-340
BR Porto Alegre, BR, 90035-074
BR Rio de Janeiro, BR, 22281-100
BR Rio de Janeiro, BR, 22250-905
BR Rio de Janeiro, BR, 22775-001
BR São Paulo, BR, 01323-900
BR São Paulo, BR, 01327-001
CA, ON Brampton, ON, CA, L6R 3J7
CA, ON Toronto, ON, CA, M4N 3M5
CA, Ontario Toronto, Ontario, CA, M5G 1Z5
CA, QC Quebec, QC, CA, G1R 2J6
CA, Québec Montréal, Québec, CA, H4A 3J1
CN Baoding, CN, 071000
CN Beijing, CN, 100730
CN Beijing, CN, 100044
CN Beijing, CN, 100034
CN Beijing, CN, 100005
CN Beijing, CN, 100142
CN Beijing, CN, 100050
CN Beijing, CN, 101199
CN Bengbu, CN, 233004
CN Changchun, CN, 130012
CN Changchun, CN, 130021
CN Changsha, CN, 410013
CN Chengdu, CN, 610041
CN Deyang, CN, 618000
CN Ganzhou, CN, 341099
CN Guangzhou, CN, 510180
CN Hangzhou, CN, 310022
CN Hangzhou, CN, 310003
CN Hefei, CN, 230001
CN Hengyang, CN, 421001
CN Huaian, CN, 223399
CN Jinan, CN, 250013
CN Linyi, CN, 276000
CN Luoyang, CN, 471003
CN Luzhou, CN, 646000
CN Nanchang, CN, 330006
CN Nanjing, CN, 210009
CN Shanghai, CN, 200433
CN Shantou, CN
CN Shenyang, CN, 110004
CN Shenyang, CN, 110042
CN Tianjin, CN, CN-300052
CN Tianjin, CN, 300201
CN Weifang, CN, 261000
CN Wuhan, CN, 430060
CN zhengzhou, CN, 450001
CN Zhengzhou, CN, 450000
CN Zhengzhou, CN, 450008
DE Berlin, DE, 12351
DE Berlin-Zehlendorf, DE, 14165
DE Essen, DE, 45122
DE Georgsmarienhuette, DE, 49124
DE Gießen, DE, 35392
DE Großhansdorf, DE, 22927
DE Hamburg, DE, 21075
DE Hamburg, DE, 20251
DE Löwenstein, DE, 74245
DE Nürnberg, DE, 90419
DE Oldenburg, DE, 26121
ES A Coruña, ES, 15009
ES Barakaldo, ES, 48903
ES Barcelona, ES, 08003
ES Barcelona, ES, 08041
ES El Palmar, ES, 30120
ES L'Hospitalet de Llobregat, ES, 08908
ES Madrid, ES, 28027
ES Madrid, ES, 28046
ES Majadahonda, ES, 28222
ES Malaga, ES, 29004
ES Oviedo, ES, 33006
ES Palma de Mallorca, ES, 7120
ES Pamplona, ES, 31008
ES Santander, ES, 39008
ES Santiago de Compostela-Coruña, ES, 15706
ES Sevilla, ES, 41014
ES Valencia, ES, 46010
ES Valencia, ES, 46026
ES Valladolid, ES, 47003
FR ANGERS Cedex 9, FR, 49933
FR Avignon, FR, 84902
FR Bordeaux, FR, 33076
FR Caen, FR, 14000
FR Lille Cedex, FR, 59037
FR Montpellier, FR, 34298
FR NANTES, FR, 44093
FR Paris, FR, 75970
FR Paris Cedex 14, FR, 75014
FR Pessac, FR, 33604
FR TOULON ARMEES, FR, 83800
FR Toulouse, FR, 31400
FR Tours, FR, 37000
FR Villejuif Cedex, FR, 94805
GB Birmingham, GB, B9 5SS
GB Cambridge, GB, CB2 0QQ
GB Glasgow, GB, G12 0YN
GB Leicester, GB, LE1 5WW
GB London, GB, EC1A 7BE
GB Manchester, GB, M20 4BX
GB Middlesbrough, GB, TS4 3BW
GR Athens, GR, 11527
GR Athens, GR, 11526
GR Athens, GR, 18547
GR Athens, GR, 12462
GR Heraklion, GR, 71110
GR Thessaloniki, GR, 552 36
GR Thessaloniki, GR, 57001
GR Thessaloniki, GR, 56249
GR Thessaloniki, GR, 57010
HK HKG, HK, 999077
HK Hong Kong, HK
HK Hong Kong, HK, 999077
HK Hong Kong, HK, HKG
HK Shatin, HK, 00000
IL Beer Sheva, IL, 8410101
IL Haifa, IL, 3109601
IL Haifa, IL, 34362
IL Jerusalem, IL, 91031
IL Jerusalem, IL, 91120
IL Kfar-Saba, IL, 4428164
IL Petah-Tikva, IL, 49100
IL Ramat Gan, IL, 52621
IL Tel Aviv, IL, 62748
IN Amravati, IN, 444606
IN Bhubaneswar, IN, 751019
IN Hyderabad, IN, 500034
IN Kolhapur, IN, 416234
IN Mumbai, IN, 400012
IN Mysuru, IN, 570017
IN Namakkal, IN, 637001
IN Pune, IN, 411001
IN Raipur, IN, 492001
IN Rajasthan, IN, 313001
IN Ranchi, IN, 834001
IN Thane, IN, 401107
IN Trivandrum, IN, 695011
IN Varanasi, IN, 221005
IT Bari, IT, 70124
IT Milano, IT, 20141
IT Misterbianco, IT, 95045
IT Monza, IT, 20090
IT Napoli, IT, 80131
IT Orbassano, IT, 10043
IT Padova, IT, 35128
IT Parma, IT, 43126
IT Perugia, IT, 06100
IT Roma, IT, 00144
IT Rozzano, IT, 20089
IT Verona, IT, 37126
JP Bunkyo-ku, JP, 113-8431
JP Bunkyo-ku, JP, 113-8603
JP Fukuoka-shi, JP, 812-8582
JP Hiroshima-shi, JP, 734-8551
JP Iruma-Gun, JP, 350-0495
JP Iwakuni-shi, JP, 740-8510
JP Kobe, JP, 650-0046
JP Koto-ku, JP, 135-8550
JP Kumamoto-shi, JP, 860-8556
JP Kyoto-shi, JP, 602-8566
JP Matsuyama-shi, JP, 791-0280
JP Nagoya-shi, JP, 466-8560
JP Nagoya-shi, JP, 464-8681
JP Niigata-shi, JP, 951-8566
JP Osaka-Sayama, JP, 589-8511
JP Osaka-shi, JP, 534-0021
JP Osaka-shi, JP, 541-8567
JP Sendai-shi, JP, 981-0914
JP Sunto-gun, JP, 411-8777
JP Toyoake-shi, JP, 470-1192
JP Utsunomiya-shi, JP, 320-0834
JP Wakayama-shi, JP, 641-8510
JP Yokohama-shi, JP, 236-0051
JP Yokohama-shi, JP, 241-8515
KR Busan, KR, 48108
KR Chungcheongbuk-do, KR, 28644
KR Goyang-si, KR, 10408
KR Gyeonggi-do, KR, 13620
KR Jinju-si, KR, 52727
KR Seoul, KR, 06351
KR Seoul, KR, 06591
KR Seoul, KR, 03722
KR Seoul, KR, 5505
KR Seoul, KR, 03080
KR Suwon-si, KR, 16247
MY Alor Setar, MY, 05460
MY Cheras, MY, 56000
MY Johor Bahru, MY, 81100
MY Kuala Lumpur, MY, 59100
MY Kuching, MY, 93586
MY Perai, MY, 13700
MY Petaling Jaya, MY, 47500
MY Selangor, MY, 46050
PH Bacolod, PH, 6100
PH Cebu City, PH, 6000
PH Davao City, PH, 8000
PH Manila, PH, 1000
PH Quezon, PH, 1104
PH Quezon, PH, 1102
PH San Juan, PH, 1500
PL Katowice, PL, 40-519
PL Krakow, PL, 30-727
PL Łódź, PL, 90-302
PL Olsztyn, PL, 10-357
PL Poznan, PL, 60-569
SG Singapore, SG, 168583
SG Singapore, SG, 308433
SG Singapore, SG, 217562
TH Bangkok, TH, 10700
TH Bangkok, TH, 10330
TH Bangkok, TH, 10400
TH Chiang Mai, TH, 50200
TH Hat Yai, TH, 90110
TH Khon-Kaen, TH, 40002
TH Pathumthani, TH, 12120
TW Changhua City, TW, 50006
TW Kaohsiung, TW, 80756
TW New Taipei, TW, 23561
TW Taichung, TW, 40705
TW Taichung, TW, 404
TW Tainan, TW, 70403
TW Tainan City, TW, 73657
TW Taipei, TW, 112
TW Taipei, TW, 100
TW Taipei City, TW, 110
US, AR Fayetteville, AR, US, 72703
US, CA Duarte, CA, US, 91010
US, CA Fountain Valley, CA, US, 92708
US, CA La Jolla, CA, US, 92093
US, CA Los Angeles, CA, US, 90048
US, CA San Diego, CA, US, 92123
US, CO Colorado Springs, CO, US, 80909
US, CO Fort Collins, CO, US, 80528
US, FL Gainesville, FL, US, 32608
US, FL Jacksonville, FL, US, 32256
US, GA Athens, GA, US, 30607
US, IL Chicago, IL, US, 60611
US, IL Evanston, IL, US, 60201
US, KY Louisville, KY, US, 40207
US, MA Boston, MA, US, 02215
US, MA Boston, MA, US, 02114
US, MD Baltimore, MD, US, 21201
US, MD Bethesda, MD, US, 20817
US, MI Detroit, MI, US, 48202
US, MO Kansas City, MO, US, 64132
US, NE Omaha, NE, US, 68124
US, NJ Morristown, NJ, US, 07960
US, NJ Northfield, NJ, US, 08225
US, NY Bronx, NY, US, 10461
US, NY New York, NY, US, 10016
US, NY New York, NY, US, 10065
US, OH Maumee, OH, US, 43537
US, PA Philadelphia, PA, US, 19107
US, PA Pittsburgh, PA, US, 15232
US, TN Chattanooga, TN, US, 37404
US, TN Nashville, TN, US, 37203
US, VA Fairfax, VA, US, 22031
US, WA Seattle, WA, US, 98104
VN Hanoi, VN, 100000