Savolitinib plus osimertinib versus platinum-based doublet chemotherapy in participants with Non-Small Cell Lung Cancer who have progressed on Osimertinib treatment

Trial Identifier:	D5087C00001
Sponsor:	AstraZeneca
NCTID::	NCT05261399
Start Date:	August 2022
Primary Completion Date:	June 2025
Study Completion Date:	December 2026
Condition:	Cancer - Other; Lung Cancer

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Trial Locations

Country	Location
AR	Berazategui, AR, B1884BBF
AR	Buenos Aires, AR, C1125ABD
AR	CABA, AR, C1019ABS
AR	Florida, AR, B1602DQD
AR	La Rioja, AR, F5300COE
AR	Rosario, AR, 2123
AR	Rosario, AR, 2000
AR	San Miguel de Tucum�n, AR, 4000
AR	Viedma, AR, R8500ACE
AT	Salzburg, AT, 5020
AU	Clayton, AU, 3168
AU	Fremantle, AU, 6160
AU	Liverpool, AU, 2170
AU	Southport, AU, 4215
AU	Waratah NSW, AU, 2298
AU	Westmead, AU, 2145
BE	Bruxelles, BE, 1000
BE	Edegem, BE, B-2650
BE	Gent, BE, 9000
BE	Hasselt, BE, 3500
BE	Mons, BE, 7000
BE	Roeselare, BE, 8800
BE	Sint-Niklaas, BE, 9100
BG	Haskovo, BG, 6300
BG	Pleven, BG, 5800
BG	Plovdiv, BG, 4002
BG	Vratsa, BG, 3000
BR	Belo Horizonte, BR, 30110-022
BR	Brasilia, BR, 70390-700
BR	Cachoeiro de Itapemirim, BR, 29308-014
BR	Curitiba, BR, 80810-050
BR	Iju�, BR, 98700-000
BR	Ipatinga, BR, 35162-189
BR	Porto Alegre, BR, 90035-903
BR	Porto Alegre, BR, 90540-140
BR	Porto Alegre, BR, 90050-170
BR	Rio De Janeiro, BR, 20231-050
BR	Rio De Janeiro, BR, 22793-080
BR	Salvador, BR, 41950-610
BR	Salvador, BR, 41253-190
BR	S�o Paulo, BR, 04014-002
BR	S�o Paulo, BR, 04556-100
BR	S�o Paulo, BR, 04538-132
BR	Vit�ria, BR, 29043-260
CA, ON	Toronto, ON, CA, M5G 2M9
CA, Ontario	Toronto, Ontario, CA, M4N 3M5
CA, QC	Montreal, QC, CA, H3T 1E2
CA, QC	Montreal, QC, CA, H3T 1M5
CH	Baden, CH, CH-5405
CH	Basel, CH, 4031
CH	Z�rich, CH, 8063
CL	Santiago, CL, 7500713
CN	Baoding, CN, 71030
CN	Beijing, CN, 100036
CN	Beijing, CN, 101149
CN	Bengbu, CN, 233060
CN	Changchun, CN, 130012
CN	Changsha, CN, 41003
CN	Changsha, CN, 410011
CN	Chengdu, CN, 610041
CN	Chongqing, CN, 400016
CN	fuzhou, CN, 350011
CN	Fuzhou, CN, 350001
CN	Hangzhou, CN, 310022
CN	Hankou,Wuhan, CN, 430022
CN	Harbin, CN, 150040
CN	Hefei, CN, 230031
CN	Jinan, CN, 250022
CN	Linyi, CN, 276000
CN	Nanchang, CN, 330006
CN	Qingdao, CN, 266035
CN	Shanghai, CN, 200030
CN	Shenyang, CN, 110001
CN	Shenzhen, CN, 518020
CN	Wuhan, CN, 430079
CN	Xian, CN, 710100
CN	Xi'an, CN, 710061
CN	Xiangfan, CN, 441021
CN	Yichang, CN, 443003
CN	Zhengzhou, CN, 450008
DE	Berlin, DE, 13353
DE	Berlin, DE, 14165
DE	Chemnitz, DE, 09113
DE	Frankfurt A. Main, DE, 60590
DE	Gauting, DE, 82131
DE	Immenhausen, DE, 34376
DE	L�wenstein, DE, 74245
DE	M�nchen, DE, 81925
DE	Muenster, DE, 48149
DE	Wangen, DE, 88239
ES	Badajoz, ES, 6006
ES	Badalona, ES, 8916
ES	Barcelona, ES, 08036
ES	Barcelona, ES, 8035
ES	Cordoba, ES, 14004
ES	Girona, ES, 17007
ES	La Coru�a, ES, 15006
ES	Madrid, ES, 28040
ES	Madrid, ES, 28041
ES	Majadahonda, ES, 28222
ES	M�laga, ES, 29010
ES	Pontevedra, ES, 36312
ES	Sabadell, ES, 08208
ES	Sevilla, ES, 41009
ES	Valencia, ES, 46026
ES	Zaragoza, ES, 50009
FR	Angers, FR, 49933
FR	Bobigny, FR, 93000
FR	Bordeaux Cedex, FR, 33076
FR	BREST, FR, 29200
FR	Creteil, FR, 94010
FR	Dijon, FR, 21079
FR	Marseille, FR, 13915
FR	Paris, FR, 75005
FR	PARIS, FR, 75018
FR	POITIERS, FR, 86021
FR	RENNES, FR, 35033
FR	Rouen, FR, 76000
FR	Saint-Herblain, FR, 44800
FR	Saint-Quentin, FR, 02321
FR	Strasbourg Cedex, FR, 67091
FR	Suresnes Cedex, FR, 92151
GB	Bristol, GB, BS2 8HW
GB	London, GB, SE1 9RT
GB	Manchester, GB, M20 4BX
GB	Wolverhampton, GB, WV10 0QP
GR	Athens, GR, 11527
GR	Athens, GR, 115 27
GR	Chaidari, GR, 124 62
GR	Heraklion, GR, 71110
GR	Larissa, GR, 41110
GR	Rio, GR, 265 04
GR	Thessaloniki, GR, 546 39
GR	Thessaloniki, GR, 54622
HK	HKG, HK, 999077
HK	Hong Kong, HK, 999077
HK	Kowloon, HK
IL	Afula, IL, 18341
IL	Ashdod, IL, 7747629
IL	Be'er Ya'akov, IL, 70300
IL	Hadera, IL, 38100
IL	Jerusalem, IL, 91031
IL	Tel Aviv, IL, 6423906
IT	Avellino, IT, 83100
IT	Aviano, IT, 33081
IT	CATANIA, IT, 95123
IT	Meldola, IT, 47014
IT	Milan, IT, 20141
IT	Milano, IT, 20133
IT	MODENA, IT, 41124
IT	MONSERRATO, IT, 09042
IT	Napoli, IT, 80138
IT	Orbassano, IT, 10043
IT	Padova, IT, 35128
IT	Parma, IT, 43126
IT	Perugia, IT, 6124
IT	PESCHIERA DEL GARDA, IT, 37019
IT	Roma, IT, 00144
IT	Roma, IT, 00152
IT	Treviso, IT, 31100
JP	Bunkyo-ku, JP, 113-8603
JP	Chuo-ku, JP, 104-0045
JP	Fukuoka-shi, JP, 812-8582
JP	Hirosaki-shi, JP, 036-8563
JP	Hiroshima-shi, JP, 730-8518
JP	Iwakuni-shi, JP, 740-8510
JP	Kanazawa-shi, JP, 920-8641
JP	Kashiwa, JP, 277-8577
JP	Kobe, JP, 650-0046
JP	Kobe-shi, JP, 650-0017
JP	Kumamoto-shi, JP, 860-8556
JP	Kurume-shi, JP, 830-0011
JP	Nagasaki-shi, JP, 852-8501
JP	Okayama-shi, JP, 700-8558
JP	Osakasayama-shi, JP, 589-8511
JP	Osaka-shi, JP, 534-0021
JP	Sakai-shi, JP, 591-8555
JP	Sapporo-shi, JP, 060-8638
JP	Sapporo-shi, JP, 003-0804
JP	Sendai-shi, JP, 980-0873
JP	Sunto-gun, JP, 411-8777
JP	Utsunomiya-shi, JP, 320-0834
JP	Wakayama-shi, JP, 641-8510
JP	Yokohama-shi, JP, 241-8515
KR	Goyang-si, KR, 10408
KR	Gyeonggi-do, KR, 13620
KR	Incheon, KR, 21431
KR	Jinju-si, KR, 660-702
KR	Seoul, KR, 06351
KR	Seoul, KR, 138-736
KR	Seoul, KR, 08308
KR	Seoul, KR, 06273
KR	Seoul, KR, 6591
KR	Suwon, KR, 16247
MY	Kota Bharu, MY, 15586
MY	Kuala Lumpur, MY, 59100
MY	Petaling Jaya, MY, 47500
MY	Pulau Pinang, MY, 10990
MY	SABAH, MY, 88996
PH	Bacolod, PH, 6100
PH	Baguio City, PH, 2600
PH	Cebu, PH, 6000
PH	Davao City, PH, 8000
PH	Manila, PH, 1000
PH	Quezon City, PH, 1112
PH	Quezon City, PH, 1104
PH	Quezon City, PH, 1100
PH	San Juan, PH, 1502
PL	Bialystok, PL, 15-003
PL	L�dz, PL, 93-338
PL	Olsztyn, PL, 10-357
SG	Singapore, SG, 308433
SG	Singapore, SG, 169610
TH	Bangkok, TH, 10210
TH	Bangkok, TH, 10700
TH	Chiang Mai, TH, 50200
TH	Dusit, TH, 10300
TH	Hat Yai, TH, 90110
TH	Muang, TH, 40002
TH	Mueang Chanthaburi, TH, 22000
TR	Adana, TR, 1370
TR	Ankara, TR, 6800
TR	Edirne, TR, 22030
TR	Istanbul, TR, 34214
TR	Istanbul, TR, 34722
TR	Izmir, TR, 35100
TW	Chiayi, TW, 62247
TW	Hsinchu, TW, 300
TW	Kaohsiung City, TW, 83301
TW	Liuying, TW, 736
TW	Taichung, TW, 40705
TW	Taichung, TW, 404
TW	Taipei, TW, 100
TW	Taipei 112, TW
TW	Taipei City, TW, 11259
US, FL	Orlando, FL, US, 32804
US, HI	Honolulu, HI, US, 96819
US, MA	Boston, MA, US, 02114
US, NJ	New Brunswick, NJ, US, 08903
US, NY	New York, NY, US, 10032
US, TN	Nashville, TN, US, 37232
VN	Can Tho, VN, 900000
VN	Hanoi, VN, 10000
VN	Hanoi, VN, 100000
VN	Hanoi city, VN, 100000
VN	Ho Chi Minh, VN, 70000
VN	Ho Chi Minh city, VN, 700000