Savolitinib plus osimertinib versus platinum-based doublet chemotherapy in participants with Non-Small Cell Lung Cancer who have progressed on Osimertinib treatment

Trial Identifier: D5087C00001
Sponsor: AstraZeneca
NCTID:: NCT05261399
Start Date: August 2022
Primary Completion Date: June 2025
Study Completion Date: December 2026
Condition: Cancer - Other; Lung Cancer

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

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Trial Locations

Country Location
AR Berazategui, AR, B1884BBF
AR Buenos Aires, AR, C1125ABD
AR CABA, AR, C1019ABS
AR Cordoba, AR, X5004APD
AR Florida, AR, B1602DQD
AR La Rioja, AR, F5300COE
AR Rosario, AR, 2123
AR Rosario, AR, 2000
AR San Miguel de Tucumán, AR, 4000
AR Viedma, AR, R8500ACE
AT Graz, AT, 8036
AT Salzburg, AT, 5020
AT Wien, AT, 1140
AU Clayton, AU, 3168
AU Fremantle, AU, 6160
AU Geelong, AU, 3220
AU Liverpool, AU, 2170
AU Southport, AU, 4215
AU Waratah NSW, AU, 2298
AU Westmead, AU, 2145
BE Bruxelles, BE, 1200
BE Bruxelles, BE, 1000
BE Edegem, BE, B-2650
BE Gent, BE, 9000
BE Hasselt, BE, 3500
BE Mons, BE, 7000
BE Roeselare, BE, 8800
BE Sint-Niklaas, BE, 9100
BG Haskovo, BG, 6300
BG Pleven, BG, 5804
BG Plovdiv, BG, 4002
BG Sofia, BG, 1407
BG Varna, BG, 9010
BG Vratsa, BG, 3000
BR Belo Horizonte, BR, 30110-022
BR Brasilia, BR, 70390-700
BR Cachoeiro de Itapemirim, BR, 29308-014
BR Curitiba, BR, 80810-050
BR Ijuí, BR, 98700-000
BR Ipatinga, BR, 35162-189
BR Porto Alegre, BR, 90035-903
BR Porto Alegre, BR, 90540-140
BR Porto Alegre, BR, 90050-170
BR Rio De Janeiro, BR, 20231-050
BR Rio De Janeiro, BR, 22793-080
BR Salvador, BR, 41950-610
BR Salvador, BR, 41253-190
BR São Paulo, BR, 04538-132
BR São Paulo, BR, 04014-002
BR São Paulo, BR, 04556-100
BR Vitória, BR, 29043-260
CA, AB Calgary, AB, CA, T2N 4N2
CA, ON Mississauga, ON, CA, L5M 2N1
CA, ON Toronto, ON, CA, M5G 2M9
CA, Ontario Toronto, Ontario, CA, M4N 3M5
CA, QC Montreal, QC, CA, H3T 1E2
CA, QC Montreal, QC, CA, H3T 1M5
CH Baden, CH, CH-5405
CH Basel, CH, 4031
CH Bern, CH, 3010
CH Winterthur, CH, 8401
CH Zürich, CH, 8063
CL Santiago, CL, 7500713
CL Santiago, CL, 7500000
CL Temuco, CL, 4800827
CN Baoding, CN, 71030
CN Beijing, CN, 100036
CN Beijing, CN, 101149
CN Bengbu, CN, 233060
CN Changchun, CN, 130012
CN Changsha, CN, 41003
CN Changsha, CN, 410013
CN Changsha, CN, 410011
CN Chengdu, CN, 610041
CN Chongqing, CN, 400016
CN fuzhou, CN, 350011
CN Fuzhou, CN, 350001
CN Hangzhou, CN, 310022
CN Hankou,Wuhan, CN, 430022
CN Harbin, CN, 150040
CN Hefei, CN, 230031
CN Jinan, CN, 250022
CN Linyi, CN, 276000
CN Nanchang, CN, 330006
CN Qingdao, CN, 266035
CN Shanghai, CN, 200030
CN Shenyang, CN, 110001
CN Shenzhen, CN, 518020
CN Wuhan, CN, 430079
CN Xian, CN, 710100
CN Xiangfan, CN, 441021
CN Yichang, CN, 443003
CN Zhengzhou, CN, 450008
DE Berlin, DE, 13353
DE Berlin, DE, 14165
DE Chemnitz, DE, 09113
DE Frankfurt A. Main, DE, 60590
DE Gauting, DE, 82131
DE Homburg, DE, 66424
DE Immenhausen, DE, 34376
DE Löwenstein, DE, 74245
DE Muenster, DE, 48149
DE München, DE, 81925
DE Stuttgart, DE, 70376
DE Wangen, DE, 88239
ES Badajoz, ES, 6006
ES Badalona, ES, 8916
ES Barcelona, ES, 08036
ES Barcelona, ES, 8035
ES Cordoba, ES, 14004
ES Girona, ES, 17007
ES La Coruña, ES, 15006
ES Madrid, ES, 28040
ES Madrid, ES, 28041
ES Majadahonda, ES, 28222
ES Málaga, ES, 29010
ES Pontevedra, ES, 36312
ES Sabadell, ES, 08208
ES Sevilla, ES, 41009
ES Valencia, ES, 46026
ES Zaragoza, ES, 50009
FR Angers, FR, 49933
FR Bobigny, FR, 93000
FR Bordeaux Cedex, FR, 33076
FR BREST, FR, 29200
FR Creteil, FR, 94010
FR Dijon, FR, 21079
FR Marseille, FR, 13915
FR Montpellier, FR, 34298
FR Paris, FR, 75005
FR PARIS, FR, 75018
FR POITIERS, FR, 86021
FR Rennes Cedex 9, FR, 35033
FR Rouen, FR, 76000
FR Saint-Herblain, FR, 44800
FR Saint-Quentin cedex, FR, 02321
FR Strasbourg Cedex, FR, 67091
FR Suresnes Cedex, FR, 92151
GB Bristol, GB, BS2 8HW
GB Leicester, GB, LE1 5WW
GB Liverpool, GB, L7 3EW
GB London, GB, SE1 9RT
GB Manchester, GB, M20 4BX
GB Newport, GB, NP10 8FZ
GB Reading, GB, RG2 9LH
GB Wolverhampton, GB, WV10 0QP
GR Athens, GR, 11527
GR Athens, GR, 115 27
GR Chaidari, GR, 124 62
GR Heraklion, GR, 71110
GR Larissa, GR, 41110
GR Rio, GR, 265 04
GR Thessaloniki, GR, 546 39
GR Thessaloniki, GR, 54622
HK HKG, HK, 999077
HK Hong Kong, HK
HK Kowloon, HK
IL Afula, IL, 18341
IL Ashdod, IL, 7747629
IL Be'er Ya'akov, IL, 70300
IL Hadera, IL, 38100
IL Jerusalem, IL, 91031
IL Tel Aviv, IL, 6423906
IT Avellino, IT, 83100
IT Aviano, IT, 33081
IT CATANIA, IT, 95123
IT Meldola, IT, 47014
IT Milan, IT, 20141
IT Milano, IT, 20133
IT MODENA, IT, 41124
IT MONSERRATO, IT, 09042
IT Napoli, IT, 80138
IT Orbassano, IT, 10043
IT Padova, IT, 35128
IT Parma, IT, 43126
IT Perugia, IT, 6124
IT PESCHIERA DEL GARDA, IT, 37019
IT Roma, IT, 00144
IT Roma, IT, 00152
IT Treviso, IT, 31100
JP Bunkyo-ku, JP, 113-8603
JP Chuo-ku, JP, 104-0045
JP Fukuoka-shi, JP, 812-8582
JP Hirosaki-shi, JP, 036-8563
JP Hiroshima-shi, JP, 730-8518
JP Iwakuni-shi, JP, 740-8510
JP Kanazawa-shi, JP, 920-8641
JP Kashiwa, JP, 277-8577
JP Kobe, JP, 650-0046
JP Kobe-shi, JP, 650-0017
JP Kumamoto-shi, JP, 860-8556
JP Kurume-shi, JP, 830-0011
JP Matsuyama, JP, 791-0288
JP Nagasaki-shi, JP, 852-8501
JP Okayama-shi, JP, 700-8558
JP Osakasayama-shi, JP, 589-8511
JP Osaka-shi, JP, 534-0021
JP Sakai-shi, JP, 591-8555
JP Sapporo-shi, JP, 060-8638
JP Sapporo-shi, JP, 003-0804
JP Sendai-shi, JP, 980-0873
JP Sunto-gun, JP, 411-8777
JP Utsunomiya-shi, JP, 320-0834
JP Wakayama-shi, JP, 641-8510
JP Yokohama-shi, JP, 241-8515
KR Goyang-si, KR, 10408
KR Gyeonggi-do, KR, 13620
KR Incheon, KR, 21431
KR Jinju-si, KR, 660-702
KR Seoul, KR, 138-736
KR Seoul, KR, 06351
KR Seoul, KR, 152703
KR Seoul, KR, 06273
KR Suwon, KR, 16247
KR Ulsan, KR, 44033
MY Kota Bharu, MY, 15586
MY Kuala Lumpur, MY, 59100
MY Pulau Pinang, MY, 10990
MY SABAH, MY, 88996
NL Amsterdam, NL, 1066CX
PH Bacolod, PH, 6100
PH Baguio City, PH, 2600
PH Cebu, PH, 6000
PH Cebu City, PH, 6000
PH Davao City, PH, 8000
PH Manila, PH, 1000
PH Quezon City, PH, 1112
PH Quezon City, PH, 1104
PH Quezon City, PH, 1100
PH San Juan, PH, 1502
PL Bialystok, PL, 15-003
PL Krakow, PL, 30-727
PL Łódź, PL, 93-338
PL Olsztyn, PL, 10-357
RU Chelyabinsk, RU, 454087
RU Moscow, RU, 119881
RU Saint Petersburg, RU, 197022
RU Tomsk, RU, 634050
SG Singapore, SG, 308433
SG Singapore, SG, 169610
TH Bangkok, TH, 10210
TH Bangkok, TH, 10700
TH Chiang Mai, TH, 50200
TH Dusit, TH, 10300
TH Hat Yai, TH, 90110
TH Muang, TH, 40002
TH Mueang Chanthaburi, TH, 22000
TR Adana, TR, 1370
TR Ankara, TR, 6800
TR Edirne, TR, 22030
TR Istanbul, TR, 34214
TR Istanbul, TR, 34722
TR Izmir, TR, 35100
TW Chiayi, TW, 62247
TW Hsinchu, TW, 300
TW Kaohsiung City, TW, 83301
TW Liuying, TW, 736
TW Taichung, TW, 40705
TW Taichung, TW, 404
TW Taipei, TW, 100
TW Taipei 112, TW
TW Taipei City, TW, 11259
US, CA La Jolla, CA, US, 92093
US, FL Orange City, FL, US, 32763
US, FL Orlando, FL, US, 32804
US, HI Honolulu, HI, US, 96819
US, IL Evergreen Park, IL, US, 60805
US, MA Boston, MA, US, 02114
US, MA Boston, MA, US, 02215
US, MI Detroit, MI, US, 48202
US, NJ Florham Park, NJ, US, 07932
US, NJ New Brunswick, NJ, US, 08903
US, NY New York, NY, US, 10032
US, OH Canton, OH, US, 44718
US, TN Nashville, TN, US, 37232
VN Can Tho, VN, 900000
VN Hanoi, VN, 10000
VN Hanoi, VN, 100000
VN Hanoi city, VN, 100000
VN Ho Chi Minh, VN, 70000
VN Ho Chi Minh city, VN, 700000