Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants with Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

Trial Identifier: D4325C00010
Sponsor: AstraZeneca
NCTID:: NCT06087835
Start Date: November 2023
Primary Completion Date: June 2027
Study Completion Date: June 2027

Available Languages

For questions about your Trial Results Summary, please see Sponsor contact section within your Trial Results Summary.

No documents have been posted yet.

Trial Locations

Country Location
AR Buenos Aires, AR, C1425AGC
AR Ciudad de Buenos Aires, AR, 1280
AR Mar del Plata, AR, B7600
AR Mar del Plata, AR, 7600
AR Rosario, AR, S2000DSV
AR Santa Fe, AR, S3000
AT Feldkirch, AT, 6800
AT Wien, AT, 1130
AU GOSFORD, AU, 2250
AU Meadowbrook, AU, 4131
AU Perth, AU, 6000
AU Reservoir, AU, 3073
AU Reservoir, AU, 3021
AU Southport, AU, 4222
BG Dobrich, BG, 9300
BG Pleven, BG, 5800
BG Plovdiv, BG, 4000
BG Sofia, BG, 1680
BG Stara Zagora, BG, 6000
BR Belem, BR, 66073-005
BR Botucatu, BR, 18618-687
BR Joinville, BR, 89227-680
BR Sao Jose Do Rio Preto, BR, 15090-000
BR São Paulo, BR, 01228-200
BR São Paulo, BR, 04038-031
BR São Paulo, BR, 04012-909
CA, ON London, ON, CA, N6A 5A5
CA, ON Waterloo, ON, CA, N2T 0C1
CA, QC Greenfield Park, QC, CA, J4V 2H1
CA, QC Montreal, QC, CA, H4J 1C5
CN Baotou, CN, 014010
CN Beijing, CN, 100035
CN Beijing, CN, 100029
CN Beijing, CN, 102218
CN Changsha, CN, 410013
CN Chengdu, CN, 610072
CN Chengdu, CN, 610000
CN Chongqing, CN, 400010
CN Deyang, CN, 618000
CN Foshan, CN, 528000
CN Guangzhou, CN, 510515
CN Guangzhou, CN, 510120
CN Hangzhou, CN, 310014
CN Hengyang, CN, 50012
CN Linhai, CN, 318000
CN nanjing, CN, 210011
CN Nanjing, CN, 210009
CN Nanning, CN, 530022
CN Ningbo, CN, 315010
CN Pingxiang, CN, 337055
CN Shanghai, CN, 200240
CN Shantou, CN, 515041
CN Shenzhen, CN, 518053
CN Shenzhen, CN, 518039
CN Wenzhou, CN, 325000
CN Wuhan, CN, 430010
CN Wuxi, CN, 214000
CN Xi 'an, CN, 710077
CN Xiamen, CN, 361101
CN Yantai, CN, 264000
CN Yibin, CN, 610500
CN Yinchuan, CN, 750004
CN Zhuzhou, CN, 412007
CN Zigong, CN, 643000
DE Aachen, DE, 52074
DE Bad Oeynhausen, DE, 32545
DE Berlin, DE, 10117
DE Fulda, DE, 36043
DE Geilenkirchen, DE, 52511
DE Hannover, DE, 30625
DE Köln, DE, 01279
DE Köln, DE, 50931
DE Mainz, DE, 55131
DE München, DE, 80336
DK Aalborg, DK, 9100
DK Aarhus, DK, 8200
DK Herlev, DK, 2730
DK Herning, DK, 7400
DK Hvidovre, DK, 2650
DK Roskilde, DK, 4000
ES Girona, ES, 17007
ES L'Hospitalet de Llobregat, ES, 08907
ES Lugo, ES, 27004
ES Madrid, ES, 28041
ES Majadahonda, ES, 28222
ES Sevilla, ES, 41071
ES Valencia, ES, 46010
FR La Tronche, FR, 38700
FR Mulhouse, FR, 68100
FR Nice, FR, 06000
FR NIMES, FR, 30000
FR ROUEN, FR, 76031
FR St-Priest-en-Jarez, FR, 42270
FR Strasbourg, FR, 67090
FR Tours, FR, 37000
GB CARDIFF, GB, CF14 4XW
GB Dundee, GB, DD1 9SY
GB Glasgow, GB, G51 4TF
GB London, GB, EC1A 2BE
GB London, GB, NW3 2QG
GB London, GB, SE5 9RJ
GB York, GB, YO21 8HE
IL Ashkelon, IL, 78278
IL Haifa, IL, 3109601
IL Jerusalem, IL, 9372212
IL Kfar-Saba, IL, 44281
IL Nahariya, IL, 22100
IL Petah Tikva, IL, 49372
IL Ramat Gan, IL, 52621
IL Rehovot, IL, 76100
IN Belagavi, IN, 590010
IT Bergamo, IT, 24127
IT Bologna, IT, 40138
IT Foggia, IT, 71100
IT Genoa, IT, 16132
IT Napoli, IT, 80138
IT Pisa, IT, 56124
IT Roma, IT, 161
IT Torino, IT, 10126
IT Viterbo, IT, 01100
JP Chuo-ku, JP, 103-0027
JP Fujisawa-shi, JP, 251-0041
JP Fukui-shi, JP, 910-8526
JP Fukuoka-shi, JP, 819-0168
JP Fukuoka-shi, JP, 810-8563
JP Fukuoka-shi, JP, 810-0001
JP Hamada-shi, JP, 697-8511
JP Hashima-gun, JP, 501-6061
JP Kamakura-shi, JP, 247-0056
JP Kasuga-shi, JP, 816-0864
JP Kawaguchi-shi, JP, 332-0012
JP Kitakyushu-shi, JP, 802-8555
JP Kitakyusyu-shi, JP, 806-8501
JP Kofu-shi, JP, 400-8506
JP Kurume-shi, JP, 830-8543
JP Kurume-shi, JP, 830-0011
JP Kusatsu-shi, JP, 525-8585
JP Kyoto-shi, JP, 607-8062
JP Matsumoto-shi, JP, 390-8510
JP Meguro-ku, JP, 153-0061
JP Minato-ku, JP, 108-0073
JP Minokamo shi, JP, 505-0010
JP Miyazaki, JP, 889-1301
JP Nishinomiya-shi, JP, 662-0971
JP Nishinomiya-Shi, JP, 662-0918
JP Okawa-shi, JP, 831-0016
JP Osaka-shi, JP, 559-0012
JP Osaka-shi, JP, 550-0006
JP Oyama-shi, JP, 323-0022
JP Saku-shi, JP, 385-8558
JP Sanuki-shi, JP, 769-2401
JP Sapporo-shi, JP, 062-0931
JP Sapporo-shi, JP, 003-0026
JP Sendai-shi, JP, 980-8574
JP Soka-shi, JP, 340-0015
JP Takamatsu-shi, JP, 760-0076
JP Takasago-shi, JP, 676-0812
JP Tondabayashi-shi, JP, 584-0082
JP Toride-shi, JP, 302-0022
JP Urayasu, JP, 279-0001
JP Utsunomiya-shi, JP, 320-8580
KR Ansan-si, KR, 15355
KR Busan, KR, 49241
KR Cheonan-si, KR, 31151
KR Daegu, KR, 41944
KR Goyang-si, KR, 10380
KR Seoul, KR, 06591
KR Seoul, KR, 156-707
KR Seoul, KR, 120-752
MX Cuautitlán, MX, 91900
MX Cuernavaca, MOR, MX, 62448
MX Mazatlán, MX, 82110
MX Mazatlán, MX, 82000
MX Mexico, MX, 14080
MX Monterrey, MX, 64460
MX Saltillo, MX, 25230
MX Veracruz, MX, 91910
MX Veracruz, MX, 91900
MY Alor Setar, MY, 5460
MY Ipoh, MY, 30990
MY Kota Kinabalu, MY, 88200
MY Kuala Lumpur, MY, 59100
MY Seremban, MY, 70300
MY Seri Manjung, MY, 32040
NL Amersfoort, NL, 3813 TZ
NL BREDA, NL, 4818 CK
NL DORDRECHT, NL, 3318 AT
NO Bodø, NO, 8073
NO Lørenskog, NO, 1478
NO Oslo, NO, 0450
NO Stavanger, NO, 4011
NO Tromsø, NO, 9019
PH Angeles City, PH, 2009
PH DAVAO DEL SUR, PH, 8000
PH Iloilo City, PH, 5000
PH Manila, PH, 1000
PH Pasig City, PH, 1605
PH Quezon City, PH, 1101
PL Chrzanów, PL, 32-500
PL Katowice, PL, 40-611
PL Krakow, PL, 31-501
PL Kraków, PL, 31-156
PL Łódź, PL, 92-213
PL Lublin, PL, 20-090
PL Poznań, PL, 60-354
PL Radom, PL, 26-600
PL Rzeszów, PL, 35-055
PL Szczecin, PL, 70-111
PL Warszawa, PL, 03-291
SE Göteborg, SE, 413 46
SE Linköping, SE, 581 85
SE Rättvik, SE, 79530
SE Stockholm, SE, 141 86
SE Uppsala, SE, 751 85
SK Kosice, SK, 04001
SK Lucenec, SK, 984 01
SK Presov, SK, 080 01
SK Puchov, SK, 020 01
SK Roznava, SK, 048 01
SK Trebišov, SK, 07501
TH Bangkok, TH, 10700
TH Bangkok, TH, 10330
TH Chaingmai, TH, 50200
TH Hat Yai, TH, 90110
TH Khon Kaen, TH, 40002
TH Ratchathewi, TH, 10400
TR Adapazarı, TR, 54100
TR Ankara, TR, 06230
TR Antalya, TR, 07100
TR Bursa, TR, 16059
TR Dinar, TR, 03400
TR Kahramanmaras, TR, 46040
TR Kayseri, TR, 38039
TR Kocaeli, TR, 41380
TW kaohsiung, TW, 807
TW Kaohsiung city, TW, 833
TW New Taipei, TW, 220
TW Taichung, TW, 40705
TW Tainan, TW, 710
TW Taipei, TW, 11490
TW Taipei, TW, 10002
TW Taipei City, TW, 110
TW Taoyuan, TW, 333
US, AL Huntsville, AL, US, 35805
US, AL Irondale, AL, US, 35210
US, AR North Little Rock, AR, US, 72114
US, AZ Sun City West, AZ, US, 85375
US, CA Bakersfield, CA, US, 93309
US, CA Huntington Park, CA, US, 90255
US, CA Los Alamitos, CA, US, 90720
US, CA Los Angeles, CA, US, 90010
US, CA Northridge, CA, US, 91324
US, CA Oxnard, CA, US, 93036
US, CA Palo Alto, CA, US, 94305
US, CA San Carlos, CA, US, 94070
US, CA San Dimas, CA, US, 91773
US, CA Tarzana, CA, US, 91356
US, CA Victorville, CA, US, 92392
US, CO Arvada, CO, US, 80002
US, CO Denver, CO, US, 80230
US, CT Hamden, CT, US, 06517
US, CT Waterbury, CT, US, 06708
US, FL Boynton Beach, FL, US, 33435
US, FL Hialeah, FL, US, 33016
US, FL Hollywood, FL, US, 33021
US, FL Hollywood, FL, US, 33024
US, FL Jacksonville, FL, US, 32204
US, FL Jensen Beach, FL, US, 34957
US, FL Miami, FL, US, 33165
US, FL Miami, FL, US, 33126
US, FL Orlando, FL, US, 32806
US, GA Atlanta, GA, US, 30345
US, GA Fayetteville, GA, US, 30214
US, IL Champaign, IL, US, 61822
US, IL Chicago, IL, US, 60612
US, IL Chicago, IL, US, 60616
US, IL Hinsdale, IL, US, 60521
US, IL Island Lake, IL, US, 60042
US, IL Skokie, IL, US, 60077
US, KY Bowling Green, KY, US, 42101
US, LA Shreveport, LA, US, 71101
US, MD Silver Spring, MD, US, 20901
US, MI Flint, MI, US, 48532
US, MI Flint, MI, US, 48504
US, MI Pontiac, MI, US, 48341
US, MI Troy, MI, US, 48098
US, MO Saint Peters, MO, US, 63376
US, NC Greenville, NC, US, 27834
US, NC Jacksonville, NC, US, 28546
US, NC Kinston, NC, US, 28504
US, NC New Bern, NC, US, 28562
US, NC Statesville, NC, US, 28625
US, NC Wilmington, NC, US, 28401
US, NC Winston Salem, NC, US, 27103
US, NY Albany, NY, US, 12205
US, NY Middletown, NY, US, 10940
US, NY Orchard Park, NY, US, 14127
US, NY Smithtown, NY, US, 11787
US, OH Maumee, OH, US, 43537
US, PA Pittsburgh, PA, US, 15243
US, PA Pottstown, PA, US, 19465
US, RI East Providence, RI, US, 02915
US, TN Bartlett, TN, US, 38133
US, TN Kingsport, TN, US, 37660
US, TX Arlington, TX, US, 76015
US, TX Austin, TX, US, 78726
US, TX Fort Worth, TX, US, 76108
US, TX Houston, TX, US, 77099
US, TX Houston, TX, US, 77004
US, TX Missouri City, TX, US, 77459
US, TX Pearland, TX, US, 77584
US, TX San Antonio, TX, US, 78204
US, TX San Antonio, TX, US, 78212
US, TX San Antonio, TX, US, 78207
US, UT Salt Lake City, UT, US, 84115
US, VA Alexandria, VA, US, 22311
US, VA Newport News, VA, US, 23606
US, WA Everett, WA, US, 98208
US, WA Spokane, WA, US, 99202
VN Ha Noi, VN, 100000
VN Hai Phong, VN, 180000
VN Ho Chi Minh, VN, 700000
VN Ho Chi Minh City, VN, 70000
VN Ho Chi Minh City, VN
ZA Benoni, ZA, 1501
ZA Cape Town, ZA, 7925
ZA Chatsworth, ZA, 4092
ZA Durban, ZA, 4450
ZA Lenasia, ZA, 1827
ZA Midrand, ZA, 1685
ZA Parow, ZA, 7505
ZA Soweto, ZA, 2013